全文获取类型
收费全文 | 12488篇 |
免费 | 1068篇 |
国内免费 | 232篇 |
专业分类
耳鼻咽喉 | 221篇 |
儿科学 | 39篇 |
妇产科学 | 41篇 |
基础医学 | 1850篇 |
口腔科学 | 695篇 |
临床医学 | 796篇 |
内科学 | 511篇 |
皮肤病学 | 35篇 |
神经病学 | 3267篇 |
特种医学 | 717篇 |
外科学 | 2061篇 |
综合类 | 1119篇 |
预防医学 | 243篇 |
眼科学 | 1444篇 |
药学 | 411篇 |
3篇 | |
中国医学 | 199篇 |
肿瘤学 | 136篇 |
出版年
2024年 | 23篇 |
2023年 | 251篇 |
2022年 | 345篇 |
2021年 | 574篇 |
2020年 | 547篇 |
2019年 | 531篇 |
2018年 | 553篇 |
2017年 | 525篇 |
2016年 | 494篇 |
2015年 | 442篇 |
2014年 | 761篇 |
2013年 | 835篇 |
2012年 | 670篇 |
2011年 | 691篇 |
2010年 | 562篇 |
2009年 | 581篇 |
2008年 | 507篇 |
2007年 | 565篇 |
2006年 | 472篇 |
2005年 | 368篇 |
2004年 | 299篇 |
2003年 | 283篇 |
2002年 | 251篇 |
2001年 | 232篇 |
2000年 | 180篇 |
1999年 | 171篇 |
1998年 | 162篇 |
1997年 | 116篇 |
1996年 | 124篇 |
1995年 | 124篇 |
1994年 | 93篇 |
1993年 | 102篇 |
1992年 | 100篇 |
1991年 | 97篇 |
1990年 | 81篇 |
1989年 | 78篇 |
1988年 | 71篇 |
1987年 | 67篇 |
1986年 | 102篇 |
1985年 | 138篇 |
1984年 | 126篇 |
1983年 | 127篇 |
1982年 | 91篇 |
1981年 | 88篇 |
1980年 | 77篇 |
1979年 | 34篇 |
1978年 | 26篇 |
1977年 | 23篇 |
1976年 | 17篇 |
1975年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 203 毫秒
51.
52.
《The Journal of arthroplasty》2022,37(5):985-992.e3
BackgroundLateral unicompartmental knee arthroplasty (UKA) is a viable solution for isolated lateral compartment arthritis. Several prosthetic designs are available such as fixed-bearing metal-backed (FB M-B), fixed-bearing all-polyethylene (FB A-P), and mobile-bearing metal-backed (MB M-B) implants. The purpose of this meta-analysis is to compare failure rates of different prosthetic designs.MethodsPreferred Reporting Items for Systematic Reviews and Meta-Analyses systematic review was conducted using 4 databases (MEDLINE, EMBASE, Cochrane, and PubMed) to identify all studies that investigate outcomes of lateral UKA. Twenty-one studies met the inclusion criteria, and failure rates were compared by implant type and follow-up time separately in order to assess potential confounding factors. Two separate analyses have been performed among different implant designs (FB M-B vs FB A-P vs MB M-B) and different follow-ups (<5 years, between 5 and 10 years, >10 years).ResultsThe failure rate of FB M-B lateral UKA was significantly lower compared to other lateral UKA designs present in the market (0.8% vs 8.6% and 7.1% for FB M-B, FB A-P, and MB M-B, respectively). No significative difference among groups has been detected when comparing all implants with regard to follow-up time.ConclusionConsidering actual evidence, for a surgeon approaching lateral UKA, the FB M-B design is preferable, given the lower failure rates and subsequently a longer implant survivorship. 相似文献
53.
目的探究会阴侧切切口感染危险因素及对患者Th1/Th2细胞因子水平的影响。方法从2018年1月-2019年1月于乳山市人民医院足月分娩行会阴侧切的产妇中随机抽样150例作为研究对象,根据是否继发切口感染,分为感染组52例和未感染组98例;制定调查表格,收集患者的临床资料,分析感染影响因素。所有受检对象均抽取外周静脉血3 ml,采用流式细胞分选技术(fluorescence-activated cell sorting,FACS)检测Th1、Th2细胞水平,计算Th1/Th2比值,采用酶联免疫吸附试验(enzyme linked immunosorbent assay,ELISA)法检测γ-干扰素(Interferon-γ,IFN-γ)、白细胞介素-4(interleukin 4,IL-4)水平,计算两者比值。结果单因素分析显示:体质量指数、产程、妊娠期糖尿病、贫血、羊水污染及感染前住院时间是产妇会阴侧切术后切口感染的影响因素(P<0.05);多因素回归显示:体质量指数≥25 kg/m^2、产程≥8 h、合并妊娠期糖尿病、贫血、羊水污染及感染前住院时间≥72 h是产妇会阴侧切术后切口感染的危险因素(P<0.05);感染组的Th1细胞(15.29±4.52)、Th2细胞(7.13±2.89)高于非感染组,而Th1/Th2比值(2.47±0.86)低于非感染组(P<0.05);感染组的血清IFN-γ(31.46±4.19)pg/ml、IL-4(23.42±2.87)pg/ml高于非感染组,而IFN-γ/IL-4(1.25±0.13)低于非感染组(P<0.05)。结论产妇会阴侧切术后切口感染的影响因素较多,应采取针对性的干预措施,降低感染发生率。侧切切口感染产妇体内存在Th细胞亚群失衡现象,炎症因子水平紊乱。 相似文献
54.
Diana Isabel Pachón-Suárez Mariana Mayorquín Ruiz Luz Elena Concha-Del-Río Rashel Cheja-Kalb Eduardo Moragrega Lourdes Arellanes-García 《Ocular immunology and inflammation》2020,28(4):626-631
ABSTRACT
Purpose
To describe the ultrabiomicroscopy (UBM) characteristics in patients with uveitic, convalescent, and recurrent Vogt-Koyanagi-Harada (VKH) disease. 相似文献55.
《The ocular surface》2020,18(2):249-257
PurposeTo evaluate the safety and effectiveness of the intranasal tear neurostimulator (ITN) in improving dry eye symptoms assessed in a controlled adverse environment (CAE®).MethodsStudy 1: Multicenter, subject-masked, randomized-sequence, crossover design. Single intranasal (active) and extranasal (control) ITN administration during CAE exposure. Study 2: Single-arm, open-label design. Intranasal ITN administration ≥2 times/day for 45 days, CAE assessment at days 0 and 45. In both studies, upon CAE entry, and every 5 min thereafter, subjects assessed eye dryness score (visual analog scale, 0–100 mm; EDS-VAS), and ocular discomfort score (ODS; Ora Calibra™, 0–4), for ≈2 h. Study 1: when ODS was ≥3 at 2 consecutive timepoints, subjects applied ITN intranasally or extranasally for ≈3 min, and again when achieving the same ODS criteria in randomized sequence. Study 2: days 0 and 45, ITN was applied for ≈3 min employing the same ODS criteria as Study 1.ResultsStudy 1: Significantly greater pre- to post-application reductions in mean [SEM] EDS (−16.5 [1.7] vs −3.1 [1.7], P < 0.0001) and ODS (−0.93 [0.08] vs −0.34 [0.08], P < 0.0001; n = 143) with intranasal vs extranasal stimulation. Study 2: On day 0 (n = 52) and day 45 (n = 48), significant pre- to post-application reductions in mean [SEM] EDS (−15.9 [2.7] and −15.2 [2.4]; P < 0.0001), and ODS (−1.3 [0.2] and −1.3 [0.1]; P < 0.0001). Few device-related adverse events were reported, none serious.ConclusionsAcute symptom relief is significant with the ITN and remains undiminished after daily use. 相似文献
56.
57.
58.
59.
60.